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The Diabetes time-tested drug Metformin appears to reduce the dreaded side effects of a cortisone treatment. Maybe a Chance of widespread cortisone, this creates anxiety in the future, something to oppose.

Against the potential side effects when taking cortisone and similar drugs, called Glucocorticoids, many patients fear: These include weight gain, a rise in blood sugar, loss of bone and muscle mass as well as increased infectious and thrombotic risk. Physicians also speak of Cushing’s syndrome. Although it is to be feared in the case of short-term application to the cortisone anxiety in long-term use of high dose tablets are quite right. Here may be emerging, however, due to Metformin, a solution, such as a study by the research group of Professor Dr. Márta Korbonits from the Queen Mary University in London showed.

In the study, 53 non-diabetic patients, which over a longer period of time, glucocorticoids revenue. The researchers tested whether the distribution of adipose tissue in the body of the participants changed when they received Metformin in addition. After 12 weeks of study duration showed that although the fat no significant differences compared to participants who were not taking Metformin, however, had improved other characteristics very well. These were values that have to do with the health of the heart and circulation, the sugar, and bone metabolism, as well as the work of the liver. At the same time increased Metformin, the anti-inflammatory main effect of glucocorticoids is even.

Metformin could represent a cost-effective way to reduce the side effects of Corticosteroids to alleviate, the study authors write in the journal The Lancet Diabetes & Endocrinology. You call for to investigate this positive effect.

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