Women Can Conceive After Surgery for Borderline Ovarian Tumors

WEDNESDAY, Oct. 7, 2020 — Natural fertility is maintained after fertility-sparing surgery (FSS) for women with borderline ovarian tumors (BOTs), with no difference in survival, according to a study published online Sept. 22 in Fertility and Sterility.

Gry Johansen, M.D., from the Karolinska University Hospital in Stockholm, and colleagues assessed the efficacy of FSS on reproductive outcomes (natural conception, use of assisted reproductive technology [ART], live birth, and obstetrical outcomes) among 277 women of reproductive age (18 to 40 years) treated in Sweden for stage I BOTs identified from the Swedish Quality Registry for Gynecologic Cancer (2008 to 2015).

The researchers found that 77 percent of the women underwent FSS, 86 percent unilateral salpingo-oophorectomy, and 14 percent cystectomy. Fifty women gave birth to 62 healthy children following FSS, with 8 percent of them delivered preterm. Only 20 women (9 percent) underwent ART treatment. Overall survival was similar between women treated with FSS and radical surgery.

“The ability to become pregnant seems to be preserved with fertility-sparing surgery, a knowledge that is absolutely critical for the advice and treatment given to young women with ovarian borderline tumors,” Johansen said in a statement.

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